“Anger is always negative”

Healthy centenarians practice elevated cognition, exalted emotions, and righteous anger - the righteous anger is important because holding resentment floods the body with cortisol and epinephrine

Dr. Northrup references Mario Martinez's study of 700 healthy centenarians who were future-oriented and lived in subcultures of wellness, noting that stress hormones directly interfere with steroid hormones like estrogen and progesterone critical for conception.